2,6-Dichloro-4-methyl-3-amino pyridine

2,6-Dichloro-4-methyl-3-amino pyridine - Names and Identifiers

Name	2,6-Dichloro-4-methyl-3-aminopyridine
Synonyms	2,6-Dichloro-4-methyl-3-pyridinamine 2,6-Dichloro-4-methylpyridin-3-amine 2,6-Dichloro-4-methyl-3-aminopyridine 2,6-Dichloro-4-methyl-3-amino pyridine 3-Pyridinamine, 2,6-dichloro-4-methyl 2,6-Dichloro-4-Methyl-pyridin-3-ylaMine 2,6-Dichloro-4-methylpyridin-3-amine, 3-Amino-2,6-dichloro-4-picoline
CAS	129432-25-3
EINECS	603-334-0
InChI	InChI=1/C6H6Cl2N2/c1-3-2-4(7)10-6(8)5(3)9/h2H,9H2,1H3

2,6-Dichloro-4-methyl-3-amino pyridine - Physico-chemical Properties

Molecular Formula	C6H6Cl2N2
Molar Mass	177.03
Density	1.414±0.06 g/cm3(Predicted)
Melting Point	83.5-85.5 °C(Solv: benzene (71-43-2))
Boling Point	327.7±37.0 °C(Predicted)
Flash Point	151.981°C
Vapor Presure	0mmHg at 25°C
pKa	0.06±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.607

2,6-Dichloro-4-methyl-3-amino pyridine - Introduction

2,6-Dichloro-4-methyl-3-aminopyridine is an organic compound with the chemical formula C7H7Cl2N. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 2,6-dichloro-4-methyl-3-aminopyridine is colorless to light yellow crystals or white particles.
-Solubility: It has high solubility in some organic solvents, such as methanol, dimethyl sulfoxide and chloroform, but low solubility in water.
-Melting point: The melting point of 2,6-dichloro-4-methyl-3-aminopyridine is about 105-108°C.

Use:
-2,6-dichloro-4-methyl-3-aminopyridine is often used as an intermediate in organic synthesis and plays an important role in the field of chemical research and medicine.
-It can be used to synthesize organic compounds such as fluorescent dyes, drugs and pesticides.

Preparation Method:
-2,6-dichloro -4-methyl -3-amino pyridine preparation methods have a variety of commonly used include:
1. reacting methyl pyridine with chloroacetic acid to obtain 2,6-dichloro -4-methyl -3-amide pyridine, which is then reacted with ammonia water to obtain the target product.
2. 2,6-dichloro-4-methylpyridine is reacted with aminoacetate to give 2,6-dichloro -4-methyl -3-aminopyridine.
3. Some other methods also include aromatic amine nucleophilic substitution.

Safety Information:
-2,6-dichloro-4-methyl-3-aminopyridine is less toxic. However, as an organic compound, it is still necessary to take appropriate safety measures when handling.
-After contact with skin or eyes, rinse immediately with plenty of water.
-Avoid inhaling dust, operate in a well-ventilated place, and wear appropriate protective equipment, such as gloves and glasses.
-Storage should be careful to avoid contact with oxidants and strong acids, stored in a dry, cool place, away from fire and high temperature.

Last Update：2024-04-09 20:45:29